Introduction
Basics
- Spread by Aedes mosquitos
- Incubation period = 2 - 14 days
Clinical features
- May cause mild flu-like illness lasting less than one week
- Classic description involves sudden onset of high fever, rigors, nausea & vomiting. Bradycardia may develop. A brief remission is followed by jaundice, haematemesis, oliguria
- If severe jaundice, haematemesis may occur
- Councilman bodies (inclusion bodies) may be seen in the hepatocytes