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Please enter at least one feature (symptom, sign or investigation result) before performing the calculation.
For example, if chest pain and low oxygen saturations were present, but haemoptysis was absent, the features section should look as follows:
To add a feature that is present, start typing and then click the green arrow.
To add the absence of a feature (i.e. a 'negative' finding), start typing then click the red cross.
If you want to remove a feature from the list simply click the grey cross in the box to the right of the feature.
Vitiligo is an autoimmune condition which results in the loss of melanocytes and consequent depigmentation of the skin. It is thought to affect around 1% of the population and symptoms typically develop by the age of 20-30 years.
Incidence: 20.00 cases per 100,000 person-years
Peak incidence: 20-30 years
Sex ratio: 1:1
Type 1 diabetes mellitus
Autoimmune thyroid disorders
Well-demarcated patches of depigmented skin
The peripheries tend to be most affected
Trauma may precipitate new lesions (Koebner phenomenon)
Sunblock for affected areas of skin
Topical corticosteroids may reverse the changes if applied early
There may also be a role for topical tacrolimus and phototherapy, although caution needs to be exercised with light-skinned patients