Introduction
Rifampicin is an antibiotic which is used to treat a variety of infections. It is frequently used to treat tuberculosis (in combination with other medications).
Rifampicin can also be used for prophylaxis in those who have had close contact with tuberculosis or meningitis.
Rifampicin can also be used for prophylaxis in those who have had close contact with tuberculosis or meningitis.
Mechanism of action
Inhibits bacterial DNA dependent RNA polymerase preventing transcription of DNA into mRNA
Indications
Tuberculosis.
Rifampicin can also be used for prophylaxis in those who have had close contact with tuberculosis or meningitis.
Rifampicin can also be used for prophylaxis in those who have had close contact with tuberculosis or meningitis.
Adverse effects
- Potent liver enzyme inducer
- Hepatitis, orange secretions
- Flu-like symptoms