Introduction
Recommended initial settings for bi-level pressure support in COPD
- Expiratory Positive Airway Pressure (EPAP): 4-5 cm H2O
- Inspiratory Positive Airway Pressure (IPAP): RCP advocate 10 cm H20 whilst BTS suggest 12-15 cm H2O
- back up rate: 15 breaths/min
- back up inspiration:expiration ratio: 1:3
Indications
- COPD with respiratory acidosis pH 7.25-7.35*
- type II respiratory failure secondary to chest wall deformity, neuromuscular disease or obstructive sleep apnoea
- cardiogenic pulmonary oedema unresponsive to CPAP
- weaning from tracheal intubation
*the BTS guidelines state that NIV can be used in patients who are more acidotic (i.e. pH < 7.25) but that a greater degree of monitoring is required (e.g. HDU) and a lower threshold for intubation and ventilation should be used