Cytomegalovirus retinitis


Cytomegalovirus (CMV) retinitis is common, affecting 30-40% of patients who have a CD4 count < 50. Diagnosis is clinical as there are no diagnostic tests

Clinical features

  • Visual impairment - 'blurred vision' etc

  • Characteristic appearance showing retinal haemorrhages and necrosis
  • Often called 'pizza' retina


  • IV ganciclovir
  • Treatment used to be life-long but new evidence suggests that it may be discontinued once CD4 > 150 after HAART
  • Alternative: IV foscarnet or cidofovir