- usually self-limiting
- the BNF advises treatment if severe or the patient is immunocompromised. Clinical Knowledge summaries also recommend antibiotics if severe symptoms (high fever, bloody diarrhoea, or more than eight stools per day) or symptoms have last more than one week
- the first-line antibiotic is clarithromycin
- ciprofloxacin is an alternative although the BNF states that 'Strains with decreased sensitivity to ciprofloxacin isolated frequently'