Introduction

Avascular necrosis (AVN) may be defined as death of bone tissue secondary to loss of the blood supply. This leads to bone destruction and loss of joint function. It most commonly affects the epiphysis of long bones such as the femur.

Epidemiology

  • Incidence: 2.50 cases per 100,000 person-years
  • Peak incidence: 40-50 years
  • Sex ratio: more common in males 4:1
Condition Relative
incidence
Greater trochanteric pain syndrome120.00
Acetabular labral tear20.00
Osteomyelitis8.00
Avascular necrosis of the hip1
<1 1-5 6+ 16+ 30+ 40+ 50+ 60+ 70+ 80+

Aetiology

Causes
  • long-term steroid use
  • chemotherapy
  • alcohol excess
  • trauma

Clinical features

Features
  • initially asymptomatic
  • pain in the affected joint

Investigations

Investigation
  • plain x-ray findings may be normal initially. Osteopenia and microfractures may be seen early on. Collapse of the articular surface may result in the crescent sign
  • MRI is the investigation of choice. It is more sensitive than radionuclide bone scanning

Management

Management
  • joint replacement may be necessary