Angiotensin 2 receptor blockers





Introduction

Angiotensin II receptor blockers are generally used in situations where patients have not tolerated an ACE inhibitor, usually due to the development of a cough.

Mechanism of action

Block effects of angiotensin II at the AT1 receptor

Adverse effects

Like ACE inhibitors they should be used with caution in patients with renovascular disease. Side-effects include hypotension and hyperkalaemia.